HERBALS

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HERBALS

The exact composition of an herbal product is influenced by the method of extraction. A tea will be rich in polar components because water is a polar solvent. Oil on the other hand is a non-polar solvent and it will absorb non-polar compounds. Alcohol lies somewhere in between.

Many herbs are applied topically to the skin in a variety of forms.  Essential oil extracts can be applied to the skin, usually diluted in a carrier oil (many essential oils can burn the skin or are simply too high dose used straight – diluting in olive oil or another food grade oil such as almond oil can allow these to be used safely as a topical).  Salves, oils, balms, creams and lotions are other forms of topical delivery mechanisms. Most topical applications are oil extractions of herbs. Taking a food grade oil and soaking herbs in it for anywhere from weeks to months allows certain phytochemicals to be extracted into the oil. This oil can then be made into salves, creams, lotions, or simply used as oil for topical application. Many massage oils, antibacterial salves and wound healing compounds are made this way. One can also make a poultice or compress using whole herb (or the appropriate part of the plant) usually crushed or dried and re-hydrated with a small amount of water and then applied directly in a bandage, cloth or just as is.

A number of herbs are thought to be likely to cause adverse effects.  Furthermore, “adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal. “ Proper double-blind clinical trials are needed to determine the safety and efficacy of each plant before they can be recommended for medical use.  Although many consumers believe that herbal medicines are safe because they are “natural”, herbal medicines and synthetic drugs may interact, causing toxicity to the patient. Herbal remedies can also be dangerously contaminated, and herbal medicines without established efficacy, may unknowingly be used to replace medicines that do have corroborated efficacy.

 Standardization of purity and dosage is not mandated in the United States, but even products made to the same specification may differ as a result of biochemical variations within a species of plant.  Plants have chemical defense mechanisms against predators that can have adverse or lethal effects on humans. Examples of highly toxic herbs include poison hemlock and nightshade.  They are not marketed to the public as herbs, because the risks are well known, partly due to a long and colorful history in Europe, associated with “sorcery”, “magic” and intrigue. Although not frequent, adverse reactions have been reported for herbs in widespread use.  On occasion serious untoward outcomes have been linked to herb consumption. A case of major potassium depletion has been attributed to chronic licorice ingestion, and consequently professional herbalists avoid the use of licorice where they recognize that this may be a risk. Black cohosh has been implicated in a case of liver failure. Few studies are available on the safety of herbs for pregnant women, and one study found that use of complementary and alternative medicines are associated with a 30% lower ongoing pregnancy and live birth rate during fertility treatment. Examples of herbal treatments with likely cause-effect relationships with adverse events include aconite, which is often a legally restricted herb, ayurvedic remedies, broom, chaparral, Chinese herb mixtures, comfrey, and herbs containing certain flavonoids, germander, guar gum, liquorice root, and pennyroyal.  Examples of herbs where a high degree of confidence of a risk long term adverse effects can be asserted include ginseng, which is unpopular among herbalists for this reason, the endangered herb goldenseal, milk thistle, senna, against which herbalists generally advise and rarely use, aloe vera juice, buckthorn bark and berry, cascara sagrada bark, saw palmetto, valerian, kava, which is banned in the European Union, St. John’s wort, Khat, Betel nut, the restricted herb Ephedra, and Guarana.

 There is also concern with respect to the numerous well-established interactions of herbs and drugs.  In consultation with a physician, usage of herbal remedies should be clarified, as some herbal remedies have the potential to cause adverse drug interactions when used in combination with various prescription and over-the-counter pharmaceuticals, just as a patient should inform an herbalist of their consumption of orthodox prescription and other medication.

For example, dangerously low blood pressure may result from the combination of an herbal remedy that lowers blood pressure together with prescription medicine that has the same effect. Some herbs may amplify the effects of anticoagulants. Certain herbs as well as common fruit interfere with cytochrome P450, an enzyme critical to much drug metabolism.

A herbalist is: (a) A person whose life is dedicated to the economic or medicinal uses of plants. (b) One skilled in the harvesting and collection of medicinal plants. (c)  Traditional Chinese herbalist: one who is trained or skilled in the dispensing of herbal prescriptions; traditional Chinese herb doctor. Similarly, Traditional Ayurvedic herbalist: one who is trained or skilled in the dispensing of herbal prescriptions in the Ayurvedic tradition.  (d)  One trained or skilled in the therapeutic use of medicinal plants.

Herbalists must learn many skills, including the wild-crafting or cultivation of herbs, diagnosis and treatment of conditions or dispensing herbal medication, and preparations of herbal medications. Education of herbalists varies considerably in different areas of the world. Lay herbalists and traditional indigenous medicine people generally rely upon apprenticeship and recognition from their communities in lieu of formal schooling.

In some countries formalized training and minimum education standards exist, although these are not necessarily uniform within or between countries. For example, in Australia the currently self-regulated status of the profession results in different associations setting different educational standards, and subsequently recognizing an educational institution or course of training. The National Herbalists Association of Australia is generally recognized as having the most rigorous professional standard within Australia. In the United Kingdom, the training of medical herbalists is done by state funded Universities.

In the European Union (EU), herbal medicines are now regulated under the European Directive on Traditional Herbal Medicinal Products.

In the United States, most herbal remedies are loosely regulated dietary supplements by the Food and Drug Administration.  Manufacturers of products falling into this category are not required to prove the safety or efficacy of their product; though the FDA may withdraw a product from sale should it prove harmful.

Some herbs, such as cannabis and coca, are outright banned in most countries though coca is legal in most of the South American countries where it is grown. The cannabis plant is used as a herbal medicine, and as such is legal in some parts of the world. Since 2004, the sales of ephedra as a dietary supplement are prohibited in the United States by the FDA, and subject to Schedule III restrictions in the United Kingdom.

Native Americans medicinally used about 2,500 of the approximately 20,000 plant species that are native to North America. With great accuracy, the plants they chose to use for medicine were in those families of plants that modern phytochemical studies show contains the most bioactive compounds.

 Some researchers trained in both western and traditional Chinese medicine have attempted to deconstruct ancient medical texts in the light of modern science. One idea is that the yin-yang balance, at least with regard to herbs, corresponds to the pro-oxidant and anti-oxidant balance. This interpretation is supported by several investigations of the ORAC ratings of various yin and yang herbs.

In India, Ayuruedic medicine has quite complex formulas with 30 or more ingredients, including a sizable number of ingredients that have undergone alchemical processing, chosen to balance Vata, Pitta or Kapha.

In Tamil Nadu, Tamils have their own medicinal system now popularly called Siddha medicine.  The Siddha system is entirely in the Tamil language.  It contains roughly 300,000 verses covering diverse aspects of medicine. This work includes herbal, mineral and metallic compositions used as medicine. Ayurveda is in Sanskrit, but Sanskrit was not generally used as a mother tongue and hence its medicines are mostly taken from Siddha and other local traditions.   In the book, Encounters with QI:  “The Chinese and Western medical models are like two frames of reference in which identical phenomena are studied. Neither frame of reference provides an unobstructed view of health and illness. Each is incomplete and in need of refinement.” Specifically, the traditional Chinese medical model could effect change on the recognized, and expected, phenomena of detachment to patients as people and estrangement unique to the clinical and impersonal relationships between patient and physician of the Western school of medicine.

Four approaches to the use of plants as medicine include:

 1. The magical/shamanic—almost all societies, with the exception of cultures influenced by Western-style industrialization, recognize this kind of use. The practitioner is regarded as endowed with gifts or powers that allow him/her to use herbs in a way that is hidden from the average person, and the herbs are said to affect the spirit or soul of the person.

2. The energetic—this approach includes the major systems of Traditional Chinese Medicine, Ayurveda, and Ugani.   The practitioner may have extensive training, and ideally be sensitive to energy, but need not have supernatural powers.  .

3. The functional dynamic—this approach was used by early physiomedical practitioners, whose doctrine forms the basis of contemporary practice in the UK. Herbs have a functional action, which is not necessarily linked to a physical compound, although often to a physiological function, but there is no explicit recourse to concepts involving energy.

4. The chemical—Modern practitioners – called Phytotherapists an attempt to explain herb actions in terms of their chemical constituents. It is generally assumed that the specific combinations of secondary metabolites in the plant are responsible for the activity claimed or demonstrated a concept called synergy.

Herbalists tend to use extracts from parts of plants, such as the roots or leaves but not isolate particular phytochemicals. Pharmaceutical medicine prefers single ingredients on the grounds that dosage can be more easily quantified. It is also possible to patent single compounds, and therefore generate income. Herbalists often reject the notion of a single active ingredient, arguing that the different phytochemicals present in many herbs will interact to enhance the therapeutic effects of the herb and dilute toxicity.  Furthermore, they argue that a single ingredient may contribute to multiple effects. Herbalists deny that herbal synergism can be duplicated with synthetic chemicals. They argue that phytochemical interactions and trace components may alter the drug response in ways that cannot currently be replicated with a combination of a few putative active ingredients. Pharmaceutical researchers recognize the concept of drug synergism but note that clinical trials may be used to investigate the efficacy of a particular herbal preparation, provided the formulation of that herb is consistent.

 In specific cases the claims of synergy and multi-functionality have been supported by science. The open question is how widely both can be generalized. Herbalists would argue that cases of synergy can be widely generalized, on the basis of their interpretation of evolutionary history, not necessarily shared by the pharmaceutical community. Plants are subject to similar selection pressures as humans and therefore they must develop resistance to threats such as radiation, reactive oxygen species and microbial attack in order to survive. Optimal chemical defenses have been selected for and have thus developed over millions of years.   Human diseases are multifactorial and may be treated by consuming the chemical defenses that they believe to be present in herbs. Bacteria, inflammation, nutrition and ROS (reactive oxygen species) may all play a role in arterial disease.  Herbalists claim a single herb may simultaneously address several of these factors. Likewise a factor such as ROS may underlie more than one condition.  In short herbalists view their field as the study of a web of relationships rather than a quest for single cause and a single cure for a single condition.

In selecting herbal treatments herbalists may use forms of information that are not applicable to pharmacists. Because herbs can moonlight as vegetables, teas or spices they have a huge consumer base and large-scale epidemiological studies become feasible. Ethno-botanical studies are another source of information. For example, when indigenous peoples from geographically dispersed areas use closely related herbs for the same purpose that is taken as supporting evidence for its efficacy.   Herbalists contend that historical medical records and herbals are underutilized resources. They favor the use of convergent information in assessing the medical value of plants. An example would be when in-vitro activity is consistent with traditional use.

 Kathy Kiefer

One thought on “HERBALS

    Mikki said:
    June 23, 2014 at 7:08 am

    A fasciinating dizcussion is worthh comment.
    I believe tht yyou should publish moire about thhis
    topic, iit mayy not bee a taboo subhject but typlically folkis don’t
    discuss these issues. To thhe next! Besst wishes!!

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